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免疫学教研室近五年发表学术论文情况
免疫学教研室

近五年,课程组教师共发表96篇学术论文,其中SCI文章33篇,北图核心48篇(*通讯作者,**SCI论文,IF=影响因子)。

[1] Shi B, Yu J, Ma L, Ma Q, Liu C, Sun S, Ma R, XinSheng Y*. Short-term assessment of BCR repertoires of SLE patients after high dose glucocorticoid therapy with high-throughput sequencing.Springerplus. 2016, 5:75.**

[2] He Xiaoyan,Sun Suhong, Yang Weiming, Tang Wentai, Ma Rui, Zhang Tian, XinSheng Y*.TRBV gene expression in PBMCs and TILs in patients with infiltrating ductal breast carcinomas analyzed by a DNA melting curve (FQ-PCR) technique using TCR beta chain CDR3 spectratyping.Journal of Zunyi Medical University. 2016 Jan, 39:35-43.**

[3] Long Ma, Liwen Yang, Bin Shi, Xiaoyan He, Aihua Peng, Yuehong Li, Teng Zhang, Suhong Sun, Rui Ma, Xinsheng Yao*. Analyzing the CDR3 Repertoire with respect to TCR-Beta Chain V-D-J and V-J Rearrangements in Peripheral T Cells using HTS.

Scientific Reports. 2016(06 接受).** IF=5.3

[4] Tao YJ, Li YJ, Zheng W, Zhao JJ, Guo MM, Zhou Y, Qin NL, Zheng J,Xu L*.Antisense oligonucleotides against microRNA-21 reduced the proliferation and migration of human colon carcinoma cells.Cancer cell international. 2015, 15:77**

[5] Zhao J, Tao Y, Zhou Y, Qin N, Chen C, Tian D,Xu L*MicroRNA-7: a promising new target in cancer therapy. Cancer cell international 2015, 15:103.

[6] Hu Y, Wang C, Li Y, Zhao J, Chen C, Zhou Y, Tao Y, Guo M, Qin N, Ren T, Wen Z, Xu L*.MiR-21 controls in situ expansion of CCR6+ regulatory T cells through PTEN/AKT pathway in breast cancer.Immunol Cell Biol. 2015 .Mar 4. **IF=4.20

[7] Ding C,Luo J(共第一作者),Li L, Li S, Yang L, Pan H, Liu Q, Qin H, Chen C, Feng J. Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer, J Exp Clin Cancer Res, 2016, 35(1):5. **

[8] Li Z, Long M, ChunMei L, Bin S, Jiang Y, Rui M, Qingqing M, XinSheng Y*.Composition and variation analysis of TCR β-chain CDR3 repertoire in the thymus and spleen of MRL/lpr mouse at different ages.Immunogenetics. 2015 Jan;67(1):25-37. ** IF=2.49

[9] Ding C,Luo J*, Yu W, Gao S, Yang L, Chen C, Feng J: Gab2 is a novel prognostic factor for colorectal cancer patients. Int J Clin Exp Pathol. 2015, 8(3):2779-2786. **IF=1.89

[10] Ding CB, Yu WN, Feng JH,Luo JM*. Structure and function of Gab2 and its role in cancer (Review). Mol Med Rep. 2015 Jun 17. **IF=1.55

[11] Gu WG.Genome editing-based HIV therapies.Trends Biotechnol. 2015 Mar;33(3):172-9. **IF=10.04

[12] Gu WG.Liu BN, Yuan JF: Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development. Journal of drug targeting 2015, 23(2):134-139. **

[13] Gu WG. Newly approved integrase inhibitors for clinical treatment of AIDS.Biomed Pharmacother. 2014 Oct;68(8):917-21. **IF=2.11

[14] Gu WG, Zhang X, Ip DT, Yang LM, Zheng YT, Wan DC4. Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging.FEBS Lett. 2014 Sep 17;588(18):3461-8. **IF=3.34

[15] Gu WG, Liu BN, Yuan JF.Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development.J Drug Target. 2015 Feb;23(2):134-9. **IF=2.72

[16] Gu WG,IpDT,Liu SJ, Chan JH,Wang Y,Zhang X,Zheng YT,Wan DC. 1,4-bis(5-(naphthalen-1-yl) thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor. Chemico-Biological Interactions, 2014 ,213:21-27.**IF=2.97

[17] Gu WG, Chen XQ*.Targeting CCR5 for anti-HIV research.Eur J Clin Microbiol Infect Dis. 2014 Jun 11. ** IF=3.02

[18] Gu WG, Zhang X, Yuan JF. Anti-HIV Drug Development Through Computational Methods. AAPS J. 2014,16(4):674-680.**I F=4.39

[19] Zhao J, Li Y, Hu Y, Chen C, Zhou Y, Tao Y, Guo M, Qin N, Xu L*.MicroRNAs expression profile in CCR6+ regulatory T cells.PeerJ. 2014 Sep 18;2:e575.

[20] ShiB,MaL,HeX,WangX,WangP,ZhouL,YaoX*.Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST.Theor Biol Med Model.2014,11(1):30.**IF=1.46

[21] Weihong Tan,Bainan Liu(Co-first author), Adel Barsoum, Weitao Huang, JK Kolls, Paul Schwarzenberger. Requirement of TPO/c-mpl for IL-17A-induced granulopoiesis and megakaryopoiesis. Journal of Leukocyte Biology. Epub ahead of print. August 2013.** IF=4.57

[22] Liu BN, Gu WG. Immunotherapy treatments of warm autoimmune hemolytic anemia. Clin Dev Immunol. 2013;2013:561852.** IF=3.06

[23] Li Y, Wang C, Zhou Y, Liao Z, Zhu S, Hu Y, Chen C, Luo J, Wen Z,Xu L*. TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells. Canc Cell Int, 2013.13(1):90.** IF=2.09

[24] Qin A, Wen Z, Zhou Y, Li Y, Li Y, Luo J, Ren T,Xu L*.MicroRNA-126 regulates the induction and function of CD4+ Foxp3+ regulatory T cells through PI3K/AKT pathway.J Cell Mol Med. 2013;17(2):252-64.** IF=4.75

[25] Guo ZL, Wen ZK, Qin AD, Zhou Y, Ren T,Xu L*. Antisense oligonucleotides treatment enhanced the recovery of acute lung injury through IL-10 secreting M2 like macrophages-induced expansion of CD4+regulatory T cells. J Immunol, 2013, 190(8):4337-48. ** IF=5.52

[26] Wang M, Wang L, Ren T,Xu L*, Wen Z. IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells. Cancer Biol Ther. 2013;14(2):155-63 ** IF=3.28

[27] Xu L, Wen Z, Zhou Y, Liu Z, Li Q, Fei G, Luo J, Ren T. MicroRNA-7 regulated TLR9 signaling enhanced growth and metastatic potential of human lung cancer cells by altering PIK3R3/Akt pathway.Mol Bio Cell. 2013. 24(1):42-55.** IF=4.6

[28] Wen Z,Xu L, Xu W, Yin Z, Gao X, Xiong S. Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA. PLoS One. 2013;8(3):e58161.** IF=3.73

[29] He XY, Yang WM, Tang WT, Ma R, Sun YP, Wang P,Yao XS*.TRAV gene expression in PBMCs and TILs in patients with breast cancer analyzed by DNA melting curve (FQ-PCR) technique for TCR alpha chain CDR3 spectratyping. Neoplasma, 2012;59(6):693-699.** IF=1.57

[30] Xu L, Zhang T, Liu Z, Li Q, Xu Z, Ren T. Critical role of Th17 cells in development of autoimmune hemolytic anemia. Exp Hematol. 2012, 40(12):994-1004.e4. ** IF=2.91

[31] Xu L, Wang C, Zhou Y, Ren T, Wen Z. CpG oligonucleotides induce the differentiation of CD4(+)Th17 cells by triggering plasmacytoid dendritic cells in adoptively cell transfer immunotherapy. Immunol Lett. 2012; 142(1-2):55-63. ** IF=2.34

[32] Zhou JW, Ma R, Tang WT, Luo R , Luo JM,Yao XS *. Primary Exploration of the Third Complementarity Determining Region 3 Spectratyping and Molecular Features of T Cell Receptor Alpha Chain in the Peripheral Blood and Tissue of Patients with Colorectal Carcinoma.Acta Medica Mediterranea, 2011, 27: 23-30.

[33] Xu L, Xu W, Wen Z, Xiong S. In situ prior proliferation of CD4+CCR6+regulatoryT cells facilitated by TGF-secreting DCs is crucial for their enrichment and suppression in tumor immunity.PLoS One. 2011;6 (5):e20282.

[34]张滕,姚新生*。自身免疫小鼠模型T细胞受体可变区beta链(TCR V beta)偏向取用研究进展。细胞与分子免疫学杂志。2016;32。(核心期刊)

[35]张滕,姚新生*。乳腺癌小鼠模型常用品系在药物研究中的应用。

免疫学杂志。2016;32(5): 450-453。(核心期刊)

[36]秦欢,马龙,潘雨蓉,姚新生*。银屑病T细胞应答及TCR CDR3谱序研究进展。中国皮肤性病学杂志。2016。(核心期刊)

[37]段芳芳,张滕,姚新生*。非专职淋巴组织部位T细胞亚群研究概况和进展。

中国免疫学杂志。2016。(核心期刊)

[38]朱顺飞,徐林*.微小RNA在乳腺癌中的研究进展,重庆医学,2015,44(2):266-268.(核心期刊)

[39]胡燕,李永菊,陈超,朱顺飞,郭萌萌,刘思静,郑静,秦娜琳,徐林*. microRNA-126基因敲减小鼠的鉴定及其血糖水平变化.中南大学学报(医学版).2015, 40(1):12-17.(核心期刊)

[40]陈超,廖珍媛,李颖,李永菊,罗军敏,徐林*. MicroRNA-7过表达对人肺癌细胞95D凋亡的影响.肿瘤防治研究. 2015,42(2):106-110.(核心期刊)

[41]陶弋婧,赵娟娟,郭萌萌,胡艳,朱顺飞,秦娜琳,郑静,徐林*.天然CD4+CD25+调节性T细胞在胸腺中发育的研究进展.现代免疫学杂志,2015, 35(1):72-76.(核心期刊)

[42]陶弋婧,赵娟娟,李永菊,郭萌萌,周涯,秦娜琳,郑静,罗军敏,徐林*.下调miRNA-21表达对人结肠癌HCT116细胞体外生长的影响.现代免疫学.2015, 35(1):6-12.(核心期刊)

[43]徐华林,赵娟娟,郑文,卢佳,雷良玉,陶弋婧,郭萌萌,罗军敏,徐林*.微小RNA-21与肿瘤关系的研究进展.肿瘤,2015, 35(6):707-712.(核心期刊)

[44]陶弋婧,朱顺飞,陈超,赵娟娟,郭萌萌,张忆雄,秦娜林,徐林*.MicroRNA-7基因敲减对小鼠CD4+SP细胞胸腺发育的影响.中国免疫学杂志.2015, 31(9):1173-1177.(核心期刊)

[45]赵娟娟,朱顺飞,徐华林,胡燕,郭萌萌,陶弋婧,周涯,秦娜琳,郑静,徐林*. MicroRNA-7对小鼠肠系膜淋巴结T淋巴细胞组成的影响.中国免疫学杂志,2015. 31(9):1163-1168.(核心期刊)

[46]郭萌萌,赵娟娟,陶弋婧,胡燕,秦娜琳,郑静,田丹,周涯,徐林*. MicroRNA-126基因敲减小鼠腹腔巨噬细胞功能的变化及意义.现代免疫学. 2015.35(4):333-338.(核心期刊)

[47]郭萌萌,廖珍媛,赵娟娟,陶弋婧,胡燕,陈超,秦娜琳,郑静,徐林*.自身启动子调控miR-7真核表达载体的构建及其对人肺癌细胞生长、迁移和凋亡的影响.遵义医学院学报,2015. 38(3):219-225.

[48]吴丽兴,陈长镜,罗军敏*. Th17细胞及其相关因子在银屑病发病中的作用及其分子机制.细胞与分子免疫学杂志,2015(2):282-284.(核心期刊).

[49].丁陈波,冯继红,于伟娜,高绍莹,徐林,陈超,罗军敏*.Gab2在结直肠癌组织中的表达及其意义.中国免疫学杂志2015, 31(2):160-162.(核心期刊)

[50]丁陈波,冯继红,罗军敏*.支架蛋白Gab2与肿瘤关系的研究进展.现代肿瘤医学,2015, 23(5):699-703.(核心期刊)

[51]于伟娜,冯继红,丁陈波,高绍莹,徐林,袁建波,罗军敏*.PRDX2基因沉默促进结直肠癌细胞上皮-间质转化增强侵袭转移能力.遵义医学院学报,2015,38(1):76-82.

[52]潘娟石彬马龙姚新生*HBsAb滴度高于10000 mU/ml外周血BCR CDR3受体库的组成及特征分析中国免疫学杂志2015年03期,300-303。(核心期刊)

[53]余江姚新生*。高通量测序分析自身免疫性疾病T细胞受体β链CDR3组库的特征。贵州医药。2015,39(3):273-275。

[54]董丽霞;罗军敏;刘春梅;孙永苹;马锐;汤贤英;孙万邦;姚新生*。FQ-PCR溶解曲线技术初步分析HFRS患者PBMC中T细胞TCRα链CDR3谱系特征。遵义医学院学报。第38卷,2015年04期,363-369。

[55]杨丽文李月红姚新生*。麻风T细胞应答及TCR CDR3谱序研究进展。中国麻风皮肤病杂志。2015年第6期,347-350。 (核心期刊)

[56]胡燕,廖珍媛,陈超,秦娜琳,郑静,田丹,李永菊,朱顺飞,罗军敏,徐林*.过表达MicroRNA-7可能通过下调CGG结合蛋白1的表达抑制人肺癌细胞生长.细胞与分子免疫学杂志,2014, 30(2):125-130(核心期刊).

[57]胡燕,廖珍媛,李永菊,陈超,朱顺飞,熊思东,徐林*.真核表达载体pEGFP-C2-miR-126-sponge的构建及其表达活性研究.第三军医大学学报. 2014,36(01):33-37(核心期刊).

[58]赵娟娟,陶弋婧,郭萌萌,秦娜琳,郑静,田丹,徐林*.微RNA-7与肿瘤关系的研究进展. 肿瘤,2014,34(5): 482-486(核心期刊).

[59]胡燕,李永菊,廖珍媛,朱顺飞,熊思东,徐林*. CD4+CD25+调节性T细胞可塑性分化的研究进展.免疫学杂志,2014, 30(8): 763-766(核心期刊).

[60]李永菊,胡艳,朱顺飞,陈超,秦娜琳,郑静,罗军敏,徐林*. CCR6与免疫细胞的关联性研究进展.现代免疫学杂志,2014. 34(4):336-338.(核心期刊)

[61]李永菊,周涯,陈超,朱顺飞,胡燕,秦娜琳,郑静,徐林*. pG-miR-7-sponge转基因小鼠载体的构建及鉴定.遵义医学院学报,2014, 37(2): 34-38.

[62]陈超,赵娟娟,胡艳,郭萌萌,陶弋婧,周涯,秦娜琳,郑静,徐林*. TTF-1启动子调控microRNA-7真核表达载体的构建.遵义医学院学报,2014, 37(3): 263-270.

[63]高绍莹,秦欢,徐林*,秦娜琳,于伟娜等.热休克蛋白16.3多克隆抗体的制备[J].细胞与分子免疫学杂志, 2014,30(8):848-851(核心期刊).

[64]高绍莹,罗军敏*,秦 欢.Toll样受体信号介导细胞凋亡的研究进展[J].细胞与分子免疫学杂志,2014,30(4):440-443(核心期刊).

[65]秦欢,高绍莹,袁建波,徐林,罗军敏*.结核分枝杆菌小分子热休克蛋白16.3蛋白的原核表达及功能检测[J].细胞与分子免疫学杂志,2014,30(5):480-484(核心期刊).

[66]孙永苹,石彬,朱红倩,汤贤英,马锐,姚新生*.FQ-PCR溶解曲线技术分析白血病患者PBMC中T细胞TCRα/βCDR3谱系特征[J].遵义医学院学报,2014,37(01):39-47.

[67]石彬,姚新生*.体细胞突变在系统性红斑狼疮的自身抗体产生中的作用.中国保健营养,2014(02):872-873.

[68]朱杰华,宋胜玉,谷万港*.基于结构的HIV-1整合酶抑制剂的虚拟筛选.中国生物制品学杂志,2014,27(1):78-81(核心期刊).

[69]周丽,马龙,姚新生*.αβT细胞TCR偏向取用与SLE的研究概况.中国免疫学杂志,2013,30(4):122-128(核心期刊).

[70]张天,孙素红,姚新生*.吲哚胺-2,3双加氧酶与乳腺癌免疫耐受关系的研究进展.细胞与分子免疫学杂志,2013(08):(核心期刊).

[71]马龙,姚新生*.系统性红斑狼疮中自身反应性B细胞发生机制研究进展.中国保健营养,2013(03): 132-134.

[72]李永菊,徐林*.诱导性CD4+CD25+调节性T细胞的研究进展.细胞与分子免疫学杂志,2013,29(12):1341-1343(核心期刊).

[73]宋永祥,李颖,秦安东,廖珍媛,李永菊,罗军敏,任涛,徐林*. miRNA-7真核表达载体的构建及鉴定.西安交通大学学报(医学版), 2013.34(4):440-445(核心期刊).

[74]廖珍媛,秦娜琳,李永菊,陈超,田丹,罗军敏,徐林*. MicroRNA-126真核表达载体的构建及其表达活性鉴定.中国肿瘤生物治疗杂志,2013,20(3):287-292(核心期刊).

[75]朱顺飞,廖珍媛,胡燕,陈超,李永菊,刘思静,罗军敏,熊思东,徐林*. MicroRNA-7过表达对人肺癌细胞体内外转移的作用.遵义医学院学报,2013,36(5):401-405.

[76]朱杰华,罗军敏*,徐林,秦娜琳,秦欢,江娟,邵云浩.结核性胸膜炎患者外周血和胸水γδT和Th17细胞的频率变化及其意义.免疫学杂志,2013;29(2):142-146(核心期刊).

[77]朱杰华,罗军敏*.Th17/IL-17在结核感染中的研究进展.中国免疫学杂志,2013;29(4):434-438(核心期刊).

[78]陈松林,罗军敏*,汤贤英,姚新生,孙万邦.结核性胸膜炎患者胸水和外周血Treg细胞及DC细胞亚群的检测.中国免疫学杂志,2013,29(9):965-968(核心期刊).

[79]秦欢,罗军敏*.结核分枝杆菌耐药机制研究进展.中国病原生物学杂志,2013;8(8):759-761(核心期刊).

[80]朱杰华,罗军敏*,叶军,秦欢,江娟,邵云浩.结核性胸膜炎患者外周血及胸腔积液中CD4+和CD8+T细胞的活化分析.微生物与感染,2013,8(2):80-85.

[81]贺晓燕,王鹏,马锐,姚新生*.一月龄BALB/c小鼠胸腺、脾脏、肝脏、小肠和血液TRBV--TRBJ1-1 CDR3谱型分析.免疫学杂志, 2012,28(10):855-860(核心期刊).

[82]孙永苹,汤贤英,朱红倩,杨雪峰,姚新生*.一例弥漫性大B淋巴细胞瘤组织样本T细胞TCRα/βCDR3谱序的初步分析.遵义医学院学报,2012, 35(2) .98-103.

[83]张彦,姚新生*.前列腺癌免疫治疗的研究进展.药品评价,2012(36):14-16.

[84]秦安东,徐林*.蛋白质的棕榈酰化修饰.生命的化学,2012,32(4): 332-335(核心期刊).

[85]秦安东,徐林*. MicroRNAs与T细胞关系的研究进展.免疫学杂志,2012, 68(1):75-78(核心期刊).

[86]秦安东,李颖,罗军敏,李永菊,徐林*. DHHCs家族成员在小鼠CD4+CD25- T细胞和CD4+CD25+调节性T细胞活化中的表达及意义.遵义医学院学报,2012, 35(5):359-366.

[87]郑静,李颖,秦安东,秦娜琳,罗军敏,徐林*. miRNA-7在小鼠不同组织器官中表达的检测及其意义.遵义医学院学报,2012,35 (2):1-5.

[88]秦安东,周涯,盛美霞,费广茹,任涛,徐林*. MicroRNA-155对人肺癌95D细胞生长的影响,中国肺癌杂志, 2011,14(7):575-580.(核心期刊)

[89]秦安东,徐林*.microRNAs与肺癌关系的研究进展.肿瘤防治研究,2011, 38(6):724-727.(核心期刊)

[90]覃明,孙万邦.空肠弯曲菌pcDNA3.1(-)- peb1A介导的T细胞活化增殖研究.免疫学杂志,2011,27(10):55-59.(核心期刊)

[91]陈富超,孙万邦.重组人IL-10在毕赤酵母菌X-33的表达及其生物活性鉴定.中国免疫学杂志,2011,27(8):691-695.(核心期刊)

[92]秦娜琳,田丹,兰慧琴,孙万邦,张忆雄,罗军敏.遵义地区汉族人群流行性出血热相

关等位基因的分布.天津医药,2011,39(10):884-886.(核心期刊)

[93]叶军,罗军敏*.结核病T细胞亚群的研究进展.免疫学杂志,2011;27(5):445-447.(核心期刊)

[94]王小妹,姚新生*.巨细胞病毒抗原PP65495-503特异性细胞毒性T细胞受体互补决定区3研究概况.国际免疫学杂志, 2011,34(4):251-256.(核心期刊)

[95]王小妹,王鹏,姚新生*. B细胞BCR CDR3受体库的高通量测序分析概况.中国免疫学杂志, 2011,27(10):947-954.(核心期刊)

[96]王鹏,贺晓燕,王小妹,姚新生*. T细胞TCR CDR3受体库的高通量测序分析概

况.现代免疫学杂志, 2011,31(6):445-449.(核心期刊)

 

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